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愛別離苦 is a Buddhist term that refers to “the pain of separation from loved ones,” or “the suffering of being separated from those whom one loves.”
If you translate each character separately, you get, “love(s) separated [and] departed [yields] pain.”
The pain character can also be defined as anguish; suffering; distress; anxiety; worry; trouble; difficulty; hardship; bitterness; to suffer; anguish; distress; anxiety; worry; trouble; difficulty; bitterness; unhappiness; or misery.